Uncovering fragmentation differences in chiral biomolecules

By combining mass spectroscopy with further analytical and simulation techniques, researchers have revealed key differences in the fragmentation of dipeptide biomolecules with different chiral structures.

Investigating optical activity under an external magnetic field

Optical activity in chiral molecules has become a hot topic in physics and optics, representing the ability to manipulate the polarized state of light. Understanding how molecules rotate the plane of plane-polarized light ...

Discovery of naturally chiral surfaces for safer pharmaceuticals

In the 1960s, the sedative thalidomide was widely popular as one of the only non-barbiturate, over-the-counter sleep-aids on the market. When doctors started noticing that it also helped alleviate morning sickness in pregnant ...

Researchers access both enantiomers by varying reaction time

Homochirality is a fundamental feature of all living organism. It is well known that a pair of enantiomers of chiral drug molecules, whose structures have a non-superimposable mirror-image relationship to each other, will ...

Electrochemical reaction powers new drug discoveries

A Cornell-led collaboration is flipping the switch on traditional synthetic chemistry by using electricity to drive a new chemical reaction that previously stumped chemists who rely on conventional methods.

A fresh twist in chiral topology

The concept of chirality is well-established in science: when an object cannot be superimposed on its mirror image, both the object and its mirror image are called chiral. In the drug industry, for instance, more than 50% ...

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