Synthesis of helical ladder polymers

Researchers at Kanazawa University synthesized helical ladder polymers with a well-defined cyclic repeating unit and one-handed helical geometry, as they reported in the Journal of the American Chemical Society.

How nerve cells control misfolded proteins

Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell, and directs them toward disposal. In collaboration with the neurology department at ...

New moves for polymer chain dynamics

A technique that enables researchers to watch the motion of individual molecules within a polymer has been developed by KAUST: it challenges current thinking about polymer physics and could lead to new materials that can ...

Collective disentanglement of entangled polymers

LMU researchers have disproven the conventional theory used to explain the dynamics of polymer solutions. They show that for biopolymers collective effects facilitate chain mobility, which is reminiscent of the behavior of ...

A new approach to amplifying DNA

Analyzing DNA is useful for a number of vital applications. This includes diagnosis and monitoring of diseases, identification of criminals, and studying the function of a targeted segment of DNA. However, methods used for ...

Glycocluster design could lead to targeted drug delivery

A team led by researchers at the RIKEN Biofunctional Synthetic Chemistry Laboratory in Japan has developed a way to engineer glycan complexes—clusters of sugar chains attached to proteins or lipids—in a way that allows ...

A roundabout route to protein production

Proteins are typically encoded by linear strands of messenger RNA (mRNA). These mRNA molecules are translated into polypeptide chains by ribosomes, with each ribosomal read-through of the mRNA generating a single, discrete ...

Pathway for membrane building blocks

Biomembranes consist of a mosaic of individual, densely packed lipid molecules. These molecules are formed inside the cells. But how do these building blocks move to the correct part of the membrane? Researchers from Technische ...

Accelerating cellular assembly lines

The immune system generates antibodies to mark threats that need to be eliminated, and these protein complexes bind their targets with remarkable strength and selectivity. Scientists have learned how to generate cell lines ...

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