A bacterial toxin that acts as a mediator rather than a killer

Traditionally, bacterial toxins have been seen as killers of target cells. But is there more than meets the eye? Umeå University Professor Teresa Frisan and her team have discovered that toxin-host interactions are more ...

Thinking afresh about how cells respond to stress

Just like people, cells get stressed too. A sudden drop in oxygen, overheating, or toxins can trigger a cascade of molecular changes that lead cells to stop growing, produce stress-protective factors, and form stress granules—proteins ...

Researchers light cells using nanosheets for cancer treatment

Scientists in the Department of Biomedical Engineering at Texas A&M University are developing new ways to advance the field of regenerative medicine and cancer treatment. They are developing a 2-D nanosheet that is 1,000 ...

Cellular stress causes cancer cell chemoresistance

There is a broad range of mechanisms associated with chemoresistance, many of which to date are only poorly understood. The so-called cellular stress response—a set of genetic programs that enable the cells to survive under ...

Widespread misinterpretation of gene expression data

Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified. RNA-seq, one of the most widely used methods ...

Intracellular transport in 3-D

Ludwig Maximilian University researchers have visualized the complex interplay between protein synthesis, transport and modification.

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