Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

Ocean life may adapt to climate change, but with hidden costs

Suppose that we could watch twenty generations of whales or sharks adapting to climate change—measuring how they evolve and how their biology changes as temperatures and carbon dioxide levels rise. That could tell us a ...

SRC-3 is a key regulator of the 12-hour clock

Many people have heard of the circadian rhythms or biological processes that follow a 24-hour cycle. Sleeping at night and being awake during the day is a well-known example of a circadian rhythm. Less well known are the ...

How bacteria cope with stress

When exposed to stress, bacteria allow their metabolism to take a break during which they suppress, for example, the incorporation of proteins into membranes. Scientists from Marburg, Freiburg and Munich have discovered this ...

Fuzzy molecular threesome is basis of gene expression

Specific nuclear proteins act as a glue to pack genetic material in an absurdly small space in the human body. Proteins "gluing" DNA are called linker histones, and hold their secret in their electric charge. They are strongly ...

Using cold to enhance microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing ...

New imaging method gives live glimpse into how cells work

By combining two microscopy methods, EPFL researchers are able to see what is happening inside a cell and on its membrane simultaneously, giving unprecedented insight into the cellular processes that occur during infection, ...

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