Kinesin-5 structure opens cancer drug targets

The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis—opening new possibilities for throwing a wrench in the machine and blocking ...

Gene movements observed in vivo

Certain parts of DNA are highly mobile and their dynamic motion participates in controlling gene expression. The research team working under Maria-Elena Torres-Padilla, an Inserm research director at the Institute of Genetics ...

The role of the cellular entry point of anthrax identified

Anthrax uses a receptor on the surface of cells to inject its lethal toxins. However, the physiological function of this receptor, named Anthrax Toxin Receptor 2a (Antxr2a), remained unknown until now.

Record reaction cascade yields cancer drug candidate

(PhysOrg.com) -- New active substances can be produced quickly and efficiently with the help of reaction cascades. Once set in motion, these processes lead to the desired end product via a series of intermediate steps which ...

How a molecular traffic jam impacts cell division

Interdisciplinary research between biology and physics aims to understand the cell and how it organizes internally. The mechanisms inside the cell are very complicated. LMU biophysicist Professor Erwin Frey, who is also a ...

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