Genome damage from CRISPR/Cas9 gene editing higher than thought

Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies ...

Cellular valve structure opens up potential novel therapies

Biochemists at the University of Zurich have determined the detailed structure of a volume-regulated chloride channel. This cellular valve is activated in response to swelling to prevent the cell from bursting. The protein ...

Ionizing radiation found to soften tumor cell microenvironment

Nearly half of all cancer patients receive radiation therapy to curb the growth of malignant cells. But little is known about how ionizing radiation affects the extracellular matrix (ECM), a patchwork of proteins and other ...

Efficient technique for isolating embryonic stem cells in cows

For more than 35 years, scientists have tried to isolate embryonic stem cells in cows without much success. Under the right conditions, embryonic stem cells can grow indefinitely and make any other cell type or tissue, which ...

Seasonal images reveal the science behind stem cells

At first glance, a pair of award-winning images created by University of Southampton postgraduate researcher Catarina Moura seem to have a seasonal theme. But look more closely and you'll see that the component parts of the ...

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