'Unassuming' enzyme opens way for new medical treatments
It sounds like a plot for a Cold War thriller—training a gene to infiltrate a cell and reside there, unnoticed, until an external self-destruct signal induces it to destroy its new home.
It sounds like a plot for a Cold War thriller—training a gene to infiltrate a cell and reside there, unnoticed, until an external self-destruct signal induces it to destroy its new home.
Molecular & Computational biology
Feb 8, 2022
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10
Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...
Cell & Microbiology
Jan 24, 2022
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52
Because iPS cells can be made into just about any cell type in the body, they have great promise for cell therapies. One major problem, however, is that not all reprogramming cells successfully become iPS cells, resulting ...
Biotechnology
Jan 6, 2022
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68
The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19. A potential new route ...
Bio & Medicine
Dec 27, 2021
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New research has moved a step closer to harnessing viruses to fight bacterial infection, reducing the threat of antibiotic resistance.
Cell & Microbiology
Dec 20, 2021
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101
While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...
Biotechnology
Dec 6, 2021
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52
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection ...
Biotechnology
Oct 28, 2021
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388
Stem cell therapy requires a lot of human cells of a specific type. Shining a near-infrared laser on adult stem cells derived from human body fat makes the stem cells replicate 54% faster. Following that up with a green laser ...
Cell & Microbiology
Oct 26, 2021
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83
Viruses have a bad reputation. They are responsible for the COVID-19 pandemic and a long list of maladies that have plagued humanity since time immemorial. Is there anything to celebrate about them?
Molecular & Computational biology
Oct 20, 2021
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11
Blue light is illuminating new understanding of a key signaling pathway in embryo development, tissue maintenance and cancer genesis.
Molecular & Computational biology
Aug 17, 2021
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357