Tree of life brought to scale by Yale scientists

Examples of biological scaling are everywhere. The paw of a mouse is smaller than the human hand. Our own organs and limbs typically scale with our body size as we develop and grow.

Researchers unravel mechanisms that control cell size

Working with bacteria, a multidisciplinary team at the University of California San Diego has provided new insight into a longstanding question in science: What are the underlying mechanisms that control the size of cells?

Genome doubling, cell size and novelty

In the 2019 Coulter Review, "Polyploidy, the Nucleotype, and Novelty: The Impact of Genome Doubling on the Biology of the Cell," published in the International Journal of Plant Sciences (180:1-52), Jeff J. Doyle and Jeremy ...

Rolling dice for cell size specification in plant leaf epidermis

One of the central questions in biology is how a cell specifies its size. Because size distribution often shows a characteristically skewed pattern in a tissue, there may be some stochastic option for determining cell size. ...

A mechanical trigger for toxic tumor therapy

Cells in nearly any part of the body can become cancerous and transform into tumors. Some, like skin cancer, are relatively accessible to treatment via surgery or radiation, which minimizes damage to healthy cells; others, ...

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