Ground-breaking new Danish research has shown that the current scientific description of the human cell cycle needs to be revised. These findings could also lead to the development of new therapeutic approaches to target ...
Cell & Microbiology
Dec 8, 2015
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A research conducted by Juan Méndez, Head of the DNA Replication Group of the Spanish National Cancer Research Centre (CNIO), sheds light on the molecular mechanisms of ageing of the stem cells responsible for regenerating ...
Cell & Microbiology
Oct 15, 2015
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21
DNA—the carrier of genetic information—is constantly threatened by damage originating from exogenous and endogenous sources. Very special DNA lesions are DNA-protein crosslinks - proteins covalently linked to DNA. So ...
Cell & Microbiology
Jul 3, 2014
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Researchers at the University of Copenhagen have unveiled a profound biological process that explains how DNA can be damaged during genome replication. In addition, the scientists developed a new analytical tool to measure ...
Cell & Microbiology
Nov 21, 2013
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Recurrent infection is a common feature of persistent viral diseases. It includes episodes of high viral production interspersed by periods of relative quiescence. These quiescent or silent stages are hard to study with experimental ...
Mathematics
May 31, 2013
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The Genomic Instability Group led by researcher Óscar Fernández-Capetillo at the Spanish National Cancer Research Centre (CNIO), has for the first time obtained a panoramic photo of the proteins that take part in human ...
Cell & Microbiology
Apr 25, 2013
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USC scientists have discovered how two different structural apparatuses collaborate to protect repetitive DNA when it is at its most vulnerable – while it is being unzipped for replication.
Cell & Microbiology
Mar 7, 2013
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DNA lesions are really common —about one million individual molecular lesions per cell per day— because its long strands usually have one missing base or are damaged. These lesions can stall the DNA replication process, ...
Cell & Microbiology
Dec 3, 2012
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Researchers of the University of Zurich have discovered a new substance for labeling and visualization of DNA synthesis in whole animals. Applications for this technique include identifying the sites of virus infections and ...
Biochemistry
Dec 13, 2011
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Alone among those infected with HIV-1, so-called elite controllers spontaneously maintain undetectable levels of viral replication even absent the benefit of anti-retroviral therapy. Now Mathias Lichterfeld of the Massachusetts ...
Cell & Microbiology
Sep 19, 2011
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