Activating a new understanding of gene regulation

Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...

Grainyhead, a master regulator that controls DNA access

A team led by Prof. Stein Aerts (VIB-KU Leuven) has reported how access to relevant DNA regions is orchestrated in epithelial cells. These findings shed new light on the biological mechanisms of gene regulation and open up ...

Three genes essential for cells to tell time

One family of genes allows cells to adapt to daily changes in environmental conditions by adjusting the circadian clock responsible for regular sleep-wake cycles. The new discovery by University of Tokyo scientists reveals ...

Lab-on-a-chip for tracking single bacterial cells

Researchers at the Biozentrum of the University of Basel, together with researchers from the Max Planck Institute in Dresden, have set up a novel lab-on-a-chip with accompanying automatic analysis software. As they report ...

Physicists develop new tool that could improve cancer research

University of Arkansas physicists have developed a new way for quantifying data from microscopic observations that could help scientists better study how cancer cells respond to treatment, among other benefits. The research, ...

Scientists reveal how epigenetic changes in DNA are interpreted

A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...

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