SARS-CoV-2 uses sugars to invade human cells

Sugars found on the surface of human cells influence COVID-19 infection, according to a University of Alberta-led study that is one of the first to observe this relationship and suggests that cells in the brain might be particularly ...

Frizzleds are dynamic, molecular machines

Maria Kowalski-Jahn and Hannes Schihada, two postdocs in the Schulte laboratory, have used a novel technology of fluorescently labeling receptors with a minimally invasive technique and detecting structural rearrangements ...

New computational method opens window into immune cell behavior

Immune cells have many jobs to do: Some identify infected cells and eliminate them. Others help rein in inflammation to prevent damage to healthy tissue. And many are critical components of cancer treatment. Researchers know ...

Nanoparticles could boost cancer immunotherapy

Boosting function of natural killer cells with magnetic nanoparticles could make cancer immunotherapy more efficient, according to a Northwestern Medicine study published in ACS Nano.

How promiscuous protein droplets regulate immune genes

Biochemists at Emory are achieving insights into how an important regulator of the immune system switches its function, based on its orientation and local environment. New research demonstrates that the glucocorticoid receptor ...

How density governs receptor activation on immune cells

Scientists from within the Antibody and Vaccine Group at the University of Southampton have gained novel insights into how an important class of immune receptors called tumor necrosis factor receptors (TNFR) are activated.

How long-known genes continue to surprise researchers

The human genome was sequenced around 20 years ago. Since then, the sequence information encoding our proteins is known—at least in principle. However, this information is not continuously stored in the individual genes, ...

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