Viruses multiply by injecting their DNA into a host cell. Once it enters the intracellular fluid, this foreign material triggers a defense mechanism known as the cGAS-STING pathway. The protein cyclic GMP-AMP Synthase (cGAS), ...
Cell & Microbiology
Aug 13, 2020
0
320
Planar cell polarity (PCP), a process in which the epithelial tissues are polarized within the plane of the epithelium, plays an important role in development and organ function. Defects in PCP are associated with a variety ...
Biochemistry
Jul 8, 2020
0
96
For protein molecules that contribute to metabolism, interactions with other components of their metabolic pathway can be crucial. Scientists at the Max Planck Institute for Developmental Biology in Tübingen have now investigated ...
Biochemistry
Jul 7, 2020
0
17
Researchers have discovered a new set of signals that cells send and receive to prompt one type of fat cell to convert fat into heat. The signaling pathway, discovered in mice, has potential implications for activating this ...
Cell & Microbiology
Jun 12, 2020
0
215
Metabolic processes are especially complex in plants due to their obligate sessile lifestyle, and scientists are discovering new and surprising connections that occur within plant cells. An important metabolic route that ...
Plants & Animals
Jun 8, 2020
0
7
The capacity of a stem cell population to generate several distinct cell types in a temporally defined manner is fundamental to both organ development and homeostasis. To achieve this, stem cells must carefully balance self-renewal ...
Cell & Microbiology
Jun 5, 2020
0
2
In the last two decades, the life sciences have seen a growing partnership with information technology. The main drive behind this is the need to process and integrate enormous volumes of data from different fields including ...
Molecular & Computational biology
Jun 4, 2020
0
35
Approximately 10 percent of infants are born with a congenital heart defect, with one of the most common being persistent truncus arteriosus—a hole in the heart. In a healthy baby, deoxygenated blood is pumped through a ...
Cell & Microbiology
May 5, 2020
0
29
For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or "metabolons," in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers ...
Biochemistry
Apr 16, 2020
0
402
Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the University of California, Davis. Published March 23 in Proceedings ...
Biochemistry
Mar 24, 2020
0
332
