Scientists at the Stem Cell Research program at Boston Children's Hospital and Dana-Farber Cancer Institute/Harvard Medical School have devised a mouse model that lets researchers track every cell in the body, from the embryonic ...
Molecular & Computational biology
May 14, 2020
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68
Experimental molecular assays with single-cell resolution generate big and complex data. Researchers at Helmholtz Zentrum München and the Technical University of Munich are now presenting their computer algorithm PAGA. They ...
Biotechnology
Apr 12, 2019
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9
Technologies such as RNA sequencing are now revealing which genes are expressed in each individual cell. All cells can then be arranged systematically using similar expression profiles. Dr. Jan Philipp Junker, head of the ...
Biotechnology
Apr 10, 2018
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117
Researchers at the University of Arkansas have discovered and characterized a new organism that will help scientists understand the molecular mechanisms and ancestral genetic toolkit that enabled animals and fungi to evolve ...
Cell & Microbiology
Sep 18, 2013
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2
How a group of animals can abandon sex, yet produce more than 460 species over evolutionary time, became a little less mysterious this week with the publication of the complete genome of a bdelloid rotifer (Adineta vaga) ...
Biotechnology
Jul 22, 2013
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1
According to researchers at Boston Children's Hospital, stem cells that strongly express a gene called WNT3 are biased to develop into cells and tissues including pancreas, liver and bladder. This discovery suggests that ...
Cell & Microbiology
Jun 4, 2013
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0
Notch – the protein that can help determine cell fate – maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein – TGF beta (transforming growth factor ...
Cell & Microbiology
Nov 1, 2012
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0
In recent years, a number of controversial claims have been made about the female mammal's egg supply – that it is renewed over her adult lifetime (as opposed to the conventional understanding that she is born with all ...
Biotechnology
Feb 23, 2012
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0
Scientists call it LUCA, the Last Universal Common Ancestor, but they don't know much about this great-grandparent of all living things. Many believe LUCA was little more than a crude assemblage of molecular parts, a chemical ...
Cell & Microbiology
Oct 5, 2011
11
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Scientists have devised a method to measure the impact of age on the growth rates of cellular populations, a development that offers new ways to understand and model the growth of bacteria, and could provide new insights ...
Evolution
Sep 7, 2011
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