Making live cell microscopy affordable

Researchers in Japan have developed a low-intensity light source that allows cell biologists to visualize and handle live cells without destroying them during prolonged exposure. In addition to laying the foundation for new ...

A question of gene silencing

When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...

History of cells told through MEMOIR

Researchers have developed a new method for reading the history and "family trees" of cells. Called MEMOIR, or Memory by Engineered Mutagenesis with Optical In situ Readout, the technique can record the life history of animal ...

Undoing a hairpin doubles gene activity

Male fruit flies have one X chromosome per cell, females have two. So genes on the male X must work twice as hard to produce the same amount of protein as its female counterparts. An LMU team has found a new switch involved ...

Structure of key protein for cell division puzzles researchers

Human cell division involves hundreds of proteins at its core. Knowing the 3D structure of these proteins is pivotal to understand how our genetic material is duplicated and passed through generations. The groups of Andrea ...

The origins of a genetic switch

Cilia, microscopic whip-like organelles that protrude from the surface of many cell types, are almost ubiquitous. They are present in all eukaryotes—organisms whose cells have a nucleus—and have diversified to perform ...

The Sorting Hat: An AI-powered image classifier for cell biologists

Cell division is an important process that underlies biological growth and repair. Cell biologists track this process by observing chromosomes—structures made of DNA that contain the genetic material of an organism. Advances ...

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