A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets, University ...
Cell & Microbiology
Mar 6, 2024
0
51
It's not a hacker lab. At Brandeis University, sophisticated computational models and advances in graphical processing units are helping scientists understand the complex interplay between genomic data, virus structure and ...
Cell & Microbiology
Jun 18, 2013
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0
Most cells can defend themselves against viruses after they have been activated by the body's own messenger substances (interferons). This happens with the help of proteins that recognize invading virus components and interfere ...
Biochemistry
Jul 1, 2022
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19
Viruses are nature's Trojan horses: They gain entrance to cells, smuggle in their genetic material, and use the cell's own machinery to replicate. For decades, scientists have studied how to minimize their deleterious effects ...
Cell & Microbiology
Apr 21, 2020
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234
Each year, about 1 million individuals worldwide become infected with HIV, the virus that causes AIDS. To replicate and spread the infection, the virus must smuggle its genetic material into the cell nucleus and integrate ...
Cell & Microbiology
Jan 25, 2024
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9
A group of University of Chicago scientists announced a groundbreaking study that explores the role of a small molecule, called IP6, in building the HIV-1 virus capsid.
Molecular & Computational biology
Oct 19, 2020
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320
With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine. Vaccines work by immunizing the body against a virus to prevent infection; ...
Molecular & Computational biology
Sep 7, 2021
0
39
For millions of years, viruses have participated in a far-flung, import-export business, exchanging fragments of themselves with both viral and non-viral agents and acquiring new features. What these tiny entities lack in ...
Cell & Microbiology
Nov 2, 2020
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27
The genome of viruses is usually enclosed inside a shell called capsid. Capsids have unique mechanic properties: they have to be resistant and at the same time capable of dissolving in order to release the genome into the ...
Cell & Microbiology
Dec 10, 2013
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0
A new study in the field of biophysics has revealed how large molecules are able to enter the nucleus of a cell. A team led by Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU) has thus provided important ...
Cell & Microbiology
Aug 24, 2020
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