How a virus forms its symmetric shells

Viruses—small disease-causing parasites that can infect all types of life forms—have been well studied, but many mysteries linger. One such mystery is how a spherical virus circumvents energy barriers to form symmetric ...

Machine-learning how to create better AAV gene delivery vehicles

Adeno-associated viruses (AAVs) have become promising vehicles for delivering gene therapies to defective tissues in the human body because they are non-pathogenic and can transfer therapeutic DNA into target cells. However, ...

Supercomputing helps reveal weaknesses in HIV-1 virus

Much remains to be discovered on how the HIV-1 virus infects our cells. Scientists know that it slips past the defenses of our immune system, entering white blood cells to deliver its genetic payload and hijack the cell's ...

New findings detail structure of immature Zika virus

Researchers at Purdue University have determined the high-resolution structure of immature Zika virus, a step toward better understanding how the virus infects host cells and spreads.

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