To overcome the off-target mutations that commonly occur with CRISPR/Cas9 genome editing methods, researchers at Harvard Medical School and Massachusetts General Hospital have developed two strategies that greatly improve ...
Biotechnology
Jul 20, 2015
0
45
Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences (BOKU) in Vienna have discovered an entirely ...
Biotechnology
Jun 11, 2015
0
17
A team of researchers at the IRCM led by François Robert, PhD, uncovered a critical role for two proteins in chromatin structure. Their breakthrough, recently published in the scientific journal Molecular Cell, helps explain ...
Cell & Microbiology
May 26, 2015
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66
Stem cells, which have the potential to turn into any kind of cell, offer the tantalizing possibility of generating new tissues for organ replacements, stroke victims and patients of many other diseases. Now, scientists at ...
Cell & Microbiology
Apr 30, 2015
0
102
Maintaining the stability and the correct sequence of our genetic information is vital to the accurate transmission of our genetic code. However, in the course of replicating, our DNA frequently runs into roadblocks, arising ...
Cell & Microbiology
Apr 14, 2015
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34
Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that ...
Bio & Medicine
Mar 2, 2015
1
1549
Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often ...
Bio & Medicine
Feb 4, 2015
0
82
Using a gene-editing system originally developed to delete specific genes, MIT researchers have now shown that they can reliably turn on any gene of their choosing in living cells.
Biotechnology
Dec 10, 2014
1
0
Every single human cell contains every single human gene. But depending on the cell, only some of these genes need to be expressed or "turned on." For instance, a heart cell has all the genes needed for, say, proper kidney ...
Biochemistry
Oct 8, 2014
1
0
Mutations in the human retinoblastoma protein gene are a leading cause of eye cancer. Now, Michigan State University scientists have turned to fruit fly eyes to unlock the secrets of this important cancer gene.
Biochemistry
Sep 17, 2014
0
0
