Chemical 'nose' sniffs critical differences in DNA structures
Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they've been extremely difficult to detect—until now.
Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they've been extremely difficult to detect—until now.
Biochemistry
May 4, 2021
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158
A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.
Biochemistry
Apr 20, 2021
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2674
In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type ...
Biochemistry
Mar 29, 2021
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21
By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3-D tumor models to replicate key aspects of tumor physiology, which ...
Analytical Chemistry
Feb 22, 2021
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11
Before Wilhelm Röntgen, a mechanical engineer, discovered a new type of electromagnetic radiation in 1895, physicians could only dream of being able to see inside the body. Within a year of Röntgen's discovery, X-rays were ...
Optics & Photonics
Feb 19, 2021
5
111
There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called 'checkpoint proteins.' These ...
Bio & Medicine
Feb 2, 2021
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153
Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum ...
Biochemistry
Jan 25, 2021
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51
In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately ...
Biotechnology
Jan 18, 2021
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45
Body odor is an unpleasant smell, produced when bacteria living on the skin break down the proteins in sweat. To avoid stinking, some people apply antiperspirants that clog sweat ducts with foreign materials, such as metals, ...
Materials Science
Dec 16, 2020
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7
Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some 'undruggable' diseases, including a type of metastatic ...
Biochemistry
Dec 15, 2020
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49