First detailed look at crucial enzyme advances cancer research

In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type ...

A powerful, pocket-sized optical imager, no longer science fiction

Before Wilhelm Röntgen, a mechanical engineer, discovered a new type of electromagnetic radiation in 1895, physicians could only dream of being able to see inside the body. Within a year of Röntgen's discovery, X-rays were ...

Breast cancer-on-a-chip for testing immunotherapy drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called 'checkpoint proteins.' These ...

Turning sweat against itself with a metal-free antiperspirant

Body odor is an unpleasant smell, produced when bacteria living on the skin break down the proteins in sweat. To avoid stinking, some people apply antiperspirants that clog sweat ducts with foreign materials, such as metals, ...

Undruggable diseases gain a new RNA drug-discovery tool

Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some 'undruggable' diseases, including a type of metastatic ...

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