The path(way) less traveled in DNA double-strand break repair

BRCA1, a protein that is well-known for its role in hereditary breast cancer, is an important part of the cellular system that repairs double-strand DNA breaks. Now, researchers from Japan have discovered a new way in which ...

The importance of DNA compaction in tissue formation

Scientists led by Dr. Salvador Aznar-Benitah, head of the Stem Cells and Cancer laboratory at IRB Barcelona, have described the alterations that occur during mammary gland formation when heterochromatin (the part of DNA that ...

Breast cancer-on-a-chip for testing immunotherapy drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called 'checkpoint proteins.' These ...

Lab turns fluorescent tags into cancer killers

A Rice University lab's project to make better fluorescent tags has turned into a method to kill tumors. Switching one atom in the tag does the trick.

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