Puzzling out the structure of a molecular giant
Combining AlphaFold2 with experimental and computational techniques has helped scientists figure out the human nuclear pore complex's architecture in greater detail than ever before.
Combining AlphaFold2 with experimental and computational techniques has helped scientists figure out the human nuclear pore complex's architecture in greater detail than ever before.
Biotechnology
Jun 10, 2022
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468
Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create ...
Biochemistry
Jun 7, 2022
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72
Cells are compartmentalized by membranes, and proteins present in these membranes play an important role in transporting cellular information. For proper function of these proteins to occur, a tertiary protein structure must ...
Biochemistry
May 26, 2022
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30
A human enzyme converts chemicals produced by marine sponges and related synthetic derivatives into cell-killing compounds, shows a study published today in eLife.
Cell & Microbiology
May 11, 2022
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24
The lab of Kathy Gould, Louise B. McGavock Professor and professor of cell and developmental biology, used a multi-disciplinary approach that included structural biology, biochemistry, and molecular biology to investigate ...
Cell & Microbiology
May 9, 2022
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21
As sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment. To do so, plants have evolved distinct molecular mechanisms to sense and respond to the environment and ...
Plants & Animals
Apr 28, 2022
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94
A team of scientists led by the Leibniz Institute for Food Systems Biology at the Technical University of Munich, in cooperation with the Chair of Food Chemistry and Molecular Sensory Science at the Technical University of ...
Biochemistry
Apr 25, 2022
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36
Scientists want to increase their understanding of circadian rhythms, those internal 24-hour biological clock cycles of sleeping and waking that occur in organisms, ranging from humans to plants to fungi to bacteria. A research ...
Molecular & Computational biology
Apr 15, 2022
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17
Tetrahymena, a tiny single celled-organism, turns out to be hiding a surprising secret: it's doing respiration—using oxygen to generate cellular energy—differently from other organisms such as plants, animals or yeasts. ...
Cell & Microbiology
Mar 31, 2022
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397
It's well understood that populations of species don't distribute at random. Rather, as populations grow, individuals are organized around barriers in the landscape. This organization can be seen in, for example, the growth ...
Cell & Microbiology
Mar 22, 2022
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45