Interactions between two key structures within cells help establish the front-to-back "polarity" that is essential to cell migration, according to a new study by Weill Cornell Medicine researchers.
Cell & Microbiology
Jun 24, 2024
0
33
Pathogens are nothing if not adaptable, and their ability to protect themselves against antibiotics increasingly poses a public health concern. A research team led by Los Alamos National Laboratory has used machine learning, ...
Biochemistry
May 14, 2024
0
48
An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.
Molecular & Computational biology
Apr 23, 2024
0
45
Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate "movies" of changing protein structures and speeds of up to 50 frames per second.
Molecular & Computational biology
Apr 17, 2024
0
33
Since the 1970s, modern antibiotic discovery has been experiencing a lull. Now the World Health Organization has declared the antimicrobial resistance crisis as one of the top 10 global public health threats.
Cell & Microbiology
Apr 8, 2024
0
48
Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can ...
Cell & Microbiology
Apr 8, 2024
0
17
Researchers at the Niels Bohr Institute, University of Copenhagen and University of Southern Denmark have recently published FreeDTS—a shared software package designed to model and study biological membranes at the mesoscale—the ...
Cell & Microbiology
Mar 22, 2024
0
56
Candida albicans is a fungus that occurs naturally in the digestive tract of most people. However, the fungus is not always harmless. It can cause mild to severe infections throughout the body. A toxin, candidalysin, is involved ...
Cell & Microbiology
Mar 21, 2024
0
70
Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed ...
Biochemistry
Mar 13, 2024
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11
A new solvatochromic probe could help shed light on the relationship between lipid membrane fluidity and various cellular functions, report scientists at Tokyo Institute of Technology and Kyushu University. Thanks to an innovative ...
Biochemistry
Mar 12, 2024
0
46
