Related topics: bacteria

Anaerobic microbial iron corrosion due to conductive pili

Iron is well-known for rusting, but this doesn't just happen on contact with oxygen and water. Some bacteria are also able to decompose iron anaerobically in a process referred to as electrobiocorrosion.

Organoids revolutionize research on respiratory infections

Biofilms are highly resistant communities of bacteria that pose a major challenge in the treatment of infections. While studying biofilm formation in laboratory conditions has been extensively conducted, understanding their ...

Shedding light on the dark problem of biofilms

Bacterial biofilms are clusters of microorganisms that form on wetted surfaces virtually everywhere. They harbor pathogens that compromise water quality, and they can disrupt the operation of many different engineered systems ...

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A biofilm is an aggregate of microorganisms in which cells adhere to each other on a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance (EPS). Biofilm EPS, which is also referred to as slime (although not everything described as slime is a biofilm), is a polymeric conglomeration generally composed of extracellular DNA, proteins, and polysaccharides. Biofilms may form on living or non-living surfaces and can be prevalent in natural, industrial and hospital settings. The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single-cells that may float or swim in a liquid medium.

Microbes form a biofilm in response to many factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics. When a cell switches to the biofilm mode of growth, it undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated.

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