Scientists have caught a glimpse of the elusive toxic form of the Alzheimer's molecule, during its attempt to bore into the outer covering of a cell decoy, using a new method involving laser light and fat-coated silver nano-particles.
Bio & Medicine
Aug 25, 2015
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25
Researchers have shown that aggregation of amyloid-beta, one of two key proteins implicated in Alzheimer's disease, causes cells to overheat and "fry like eggs."
Biochemistry
May 31, 2022
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252
(PhysOrg.com) -- Which modules of the tau protein, in neurons of Alzheimer disease patients, may act in a destructive manner were investigated by researchers from the Max Planck Institute for Biophysical Chemistry (Göttingen) ...
Feb 17, 2009
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A probe invented at Rice University that lights up when it binds to a misfolded amyloid beta peptide—the kind suspected of causing Alzheimer's disease—has identified a specific binding site on the protein that could facilitate ...
Biochemistry
Oct 19, 2017
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255
Scientists from Rice University are using fluorescence lifetime to shed new light on a peptide associated with Alzheimer's disease, which the Centers for Disease Control and Prevention estimates will affect nearly 14 million ...
Biochemistry
Jan 25, 2023
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32
Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't wedge themselves in between ...
Bio & Medicine
Aug 29, 2022
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138
More than half of all cases of dementia in the elderly can be attributed to Alzheimer's disease. Despite vast research efforts, an effective therapy has not been developed, and treatment consists of dealing with the symptoms. ...
Biochemistry
Jan 12, 2012
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0
Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer's disease. Scientists say the discovery may lead to new drugs for ...
Biochemistry
Jul 1, 2009
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0
A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies—stacks of peptides that include amyloid beta, most notably associated with ...
Bio & Medicine
Apr 24, 2024
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28
A metallic molecule being studied at Rice University begins to glow when bound to amyloid protein fibrils of the sort implicated in Alzheimer's disease. When triggered with ultraviolet light, the molecule glows much brighter, ...
Biochemistry
Jul 7, 2016
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12
