Basement membrane underpins tissue interactions in the skin

In a discovery that could pave the way for therapies that promote wound healing and alleviate skin diseases, RIKEN researchers have found that the network of molecules under the outermost layer of mouse skin, the skin epithelium, ...

Why do cells make invadopodia?

During development and immune system function in animals, specialized cells acquire the ability to invade other tissues. Such invasive behavior is important for neural crest cells that invade skin and provide pigmentation, ...

Repairs in the basement membrane

Basement membrane (BM) is an evolutionarily ancient sheet-like scaffold that wraps around most animal tissues. BM protects and provides mechanical stiffness to tissues and regulates development, function, and repair. But ...

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