X-rays reveal layout of loaded drug transporter

Experiments at DESY's X-ray source PETRA III have revealed the first structure of a biological transporter protein loaded with a pro-drug. Prodrugs are inactive medications that are metabolized into an active, functional ...

New life form answers question about evolution of cells

Bacteria and Archaea are two of the three domains of life. Both must have evolved from the putative last universal common ancestor (LUCA). One hypothesis is that this happened because the cell membrane in LUCA was an unstable ...

New tool for the crystallisation of proteins

ETH researchers have developed a new method of crystallising large membrane proteins in order to determine their structure. This will be of benefit to biological research and the pharmaceutical industry.

Antibacterial applications of graphene oxides

Bacterial infections are among the greatest threats to human health. However, due to the increasing spread of multidrug-resistant bacteria, the current antibiotic supply appears to be insufficient, thereby necessitating the ...

The importance of asymmetry in bacteria

New research published in Nature Microbiology has highlighted a protein that functions as a membrane vacuum cleaner and which could be a potential new target for antibiotics.

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