Surface protein editing in bacteria

University of Minnesota researchers have discovered this previously unknown signaling pathway that regulates surface proteins on bacteria that can lead to new targets for antibiotics.

Filming how our immune system kill bacteria

To kill bacteria in the blood, our immune system relies on nanomachines that can open deadly holes in their targets. UCL scientists have now filmed these nanomachines in action, discovering a key bottleneck in the process ...

Researchers grow cells in 'paper organs'

Long before scientists test new medicines in animals or people, they study the effects of the substances on cells growing in Petri dishes. However, a 2-D layer of cells is a poor substitute for the much more complex 3-D structure ...

Bacteria uses viral weapon against other bacteria

Bacterial cells use both a virus—traditionally thought to be an enemy—and a prehistoric viral protein to kill other bacteria that competes with it for food according to an international team of researchers who believe ...

Bacteria harness viruses to distinguish friend from foe

Bacterial cells that normally colonize our guts can distinguish themselves from other bacterial species using what's traditionally considered their enemy—a virus. Researchers report April 16 in the journal Cell Reports ...

How bugs overcome host defenses

Bacterial pathogens must acquire nutrient metals from the host to survive and cause disease. To counter infection, hosts attempt to starve bacteria by hiding metals away in a process called "nutritional immunity." Bacteria ...

Research identifies potential target for strep A vaccine

Most people think of "strep throat" as a relatively benign infection cured by a round of antibiotics and a few days of rest. But the bacterium that causes strep throat—Group A Streptococcus—is also responsible for a number ...

Traffic control of cells

Cells in the human body can display remarkable differences in their behaviour depending on the mechanical properties of the tissue surrounding them. This is especially true for immune cells, which migrate through the body ...

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