In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic ...
Molecular & Computational biology
Jun 1, 2021
0
12
New research published in Science Advances provides a template for how to develop directly acting antivirals with novel modes of action that would combat COVID-19 by suppressing the SARS-CoV-2 viral infection. The study focused ...
Molecular & Computational biology
Apr 15, 2021
0
64
Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson ...
Cell & Microbiology
Mar 22, 2021
1
32
Evidence is emerging that vitamin D—and possibly vitamins K and A—might help combat COVID-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown ...
Biochemistry
Jan 29, 2021
1
2274
EPFL scientists have developed a synthetic molecule capable of killing the virus that causes influenza. They hope their discovery will lead to an effective drug treatment.
Biochemistry
Dec 15, 2020
2
152
Researchers from UCLA and China have found that catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of coronavirus inside the body. ...
Biochemistry
Sep 29, 2020
1
397
Researchers at the University of Alberta have discovered a novel, second mechanism of action by the antiviral drug remdesivir against SARS-CoV-2, according to findings published today in the Journal of Biological Chemistry.
Biochemistry
Sep 24, 2020
0
11
Inevitably, the rapid spread of an emergent and potentially lethal virus around the world has led to huge disruption of normal life. With talk of a new-normal in the wake of the COVID-19 pandemic, we do not yet have any way ...
Economics & Business
Sep 14, 2020
0
1
Exactly how viruses replicate is a complex puzzle with many missing pieces. And in the age of the pandemic, solving it has become a matter of acute urgency.
Cell & Microbiology
Aug 10, 2020
2
239
A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell. This ...
Molecular & Computational biology
Apr 20, 2020
0
5
