New research could pave the way to developing cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death. Cancer cells that are resistant to anticancer drugs are known to be vulnerable to ferroptosis. ...
Biotechnology
Apr 5, 2024
0
50
Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value. One of these hidden gems is (–)-jerantinine A (JA), a molecule with remarkable anticancer properties, ...
Biochemistry
Mar 23, 2023
0
26
As part of their efforts to devise ways to minimize the side effects of drugs for treating cancer, four RIKEN chemists have found a biocompatible way to convert compounds with low biological activity into anticancer drugs ...
Materials Science
May 18, 2021
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31
A gene called MYC has become one of the hottest targets for cancer researchers around the world. MYC is known to drive tumor growth in nearly all cancer types—but successfully targeting the gene has proven to be a challenge. ...
Biochemistry
Jul 8, 2019
0
2
After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex 'anti-tumour antibiotic' known to be highly effective against cancer cells as well as drug-resistant bacteria, and have ...
Biochemistry
Apr 24, 2019
0
258
A group of scientists from Moscow universities led by Yan Ivanenkov, the head of Laboratory of Medical Chemistry and Bioinformatics in MIPT, has succeeded in synthesizing a set of novel selenohydantoins with anticancer and ...
Biochemistry
Mar 15, 2016
0
44
Scientists identify 3D structure of enzyme critical to the creation of anticancer and antimalarial compounds in plants
Biochemistry
Nov 9, 2015
0
13
Inspired by a chemical that fungi secrete to defend their territory, MIT chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.
Biochemistry
Feb 27, 2013
1
0
A group of researchers at the University of California, Berkeley have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs.
Cell & Microbiology
Nov 15, 2012
0
0
Medical Systems Virology group at the Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki, together with its national and international collaborators, developed a new cell screening method that can ...
Biochemistry
Sep 5, 2012
0
0
