Mapping the effects of mutations in antibiotic-resistant bacteria

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic ...

Scientists produce new antibiotics by gene editing

Scientists have discovered a new route to produce complex antibiotics exploiting gene editing to re-program pathways to future medicines urgently required to combat antimicrobial resistance, treat neglected diseases and tackle ...

Differentiating strong antibiotic producers from weaker ones

An untapped trove of desirable drug-like molecules is hidden in the genomes of Streptomyces bacteria—the same bacteria responsible for the first bacterial antibiotics to treat tuberculosis back in the 1940s.

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