Amyloid probes gain powers in search for Alzheimer's cause

A metallic molecule being studied at Rice University begins to glow when bound to amyloid protein fibrils of the sort implicated in Alzheimer's disease. When triggered with ultraviolet light, the molecule glows much brighter, ...

The most complete review of the peptide behind Alzheimer's

The hope is to be able, one day, to fight the pathogenic action of the amyloid-beta protein, whose build-up is associated with Alzheimer's disease. In the meantime, scientists—including a group from the International School ...

Engineering self-assembling amyloid fibers

Nature has many examples of self-assembly, and bioengineers are interested in copying or manipulating these systems to create useful new materials or devices. Amyloid proteins, for example, can self-assemble into the tangled ...

Watching nanoscale assembly live

Ebola virus, Alzheimer's amyloid fibrils, tissue collagen scaffolds and cellular cytoskeleton are all filamentous structures that spontaneously assemble from individual proteins.

Measuring modified protein structures

Swiss researchers have developed a new approach to measure proteins with structures that change. This could enable new diagnostic tools for the early recognition of neurodegenerative diseases to be developed.

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