Overactive cell metabolism linked to biological aging

Why do cells, and by extension humans, age? The answer may have a lot to do with mitochondria, the organelles that supply cells with energy. Though that idea is not new, direct evidence in human cells had been lacking. Until ...

Enzyme 'atlas' helps researchers decipher cellular pathways

One of the most important classes of human enzymes are protein kinases—signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways ...

Team creates nano-magnets that could restore damaged nerve cells

Neurons are the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles, and for transforming and relaying the ...

Scientists unveil the functional landscape of essential genes

A team of scientists at Whitehead Institute and the Broad Institute of MIT and Harvard have systematically evaluated the functions of more than 5,000 essential human genes using a novel, pooled, imaged-based screening method. ...

Nanosensors target enzymes to monitor and study cancer

Cancer is characterized by a number of key biological processes known as the "hallmarks of cancer," which remodel cells and their immediate environment so that tumors can form, grow, and thrive. Many of these changes are ...

A new technique for observing gene activity in a test tube

When searching for the causes of illnesses and developing new treatments, it is absolutely vital to have a precise understanding of the genetic fundamentals. Würzburg researchers have devised a new technique for this purpose.

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