Search results for genome editing

Biotechnology Jan 14, 2026

CRISPR–Cas3 genome-editing system holds therapeutic potential

Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism.

Biotechnology Jan 3, 2026

A better way to detect off-target genome changes from base editors

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital. Significant amounts of time and resources spent improving CRISPR ...

Cell & Microbiology Nov 18, 2025

The genome editing playbook is different in neurons and other nondividing cells, researchers discover

The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by genetic mutations. But so far, attempts to use the technology to address brain-based genetic disorders ...

Biotechnology Nov 12, 2025

Gene editing produces plants that are indigestible to pests

Insects that feed on starch can find veritable feasts in corn, pea, and bean crops or warehouses. It is no coincidence that the ancestors of these commercial plants developed α-amylase inhibitor proteins, which make the starch ...

Biotechnology Nov 10, 2025

Phages with fully-synthetic DNA can be edited gene by gene

A team led by University of Pittsburgh's Graham Hatfull has developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at will. The findings open ...

Plants & Animals Nov 5, 2025

New method makes transgene-free gene editing even more promising

Genetically modified organisms, also known as GMOs, have been a hot topic of conversation among researchers, producers, government agencies, and the general public for decades.

Biotechnology Nov 3, 2025

Powerful tool can map gene regulation at single-nucleotide resolution

Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by chemist Brian Liau and his collaborators at Harvard offers an unprecedented window into this activity, ...

Biotechnology Oct 23, 2025

New gene-editing tech repurposes bacterial retrons to correct large stretches of DNA

Some genetic disorders—such as cystic fibrosis, hemophilia and Tay Sachs disease—involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a ...

Biotechnology Oct 14, 2025

Cracking the CRISPR code to find the 'passwords' that unlock its full potential

One of the most revolutionary tools in cutting-edge medicine is a molecular scalpel so precise that it can modify defective DNA and fix genetic diseases like sickle cell anemia, and chronic disorders like cardiovascular diseases ...

Biotechnology Oct 2, 2025

Generative AI can outperform nature at designing proteins to edit the genome

Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated ...

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