For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in the genetic code. Arc Institute researchers are changing that paradigm with a universal gene editing ...
Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes. However, adapting them for biomedical applications has been challenging.
In a development that could help protect one of the world's most beloved agricultural commodities, a research team at Penn State has successfully created disease-resistant cacao plants using gene-editing technology. According ...
A research team led by Prof. Wang Yanli from the Institute of Biophysics of the Chinese Academy of Sciences has revealed the structure and mechanism of a highly active Type II-D Cas9, offering a promising new tool for genome ...
A research team led by scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) has introduced a new way to fine-tune genetic material. Their study, published in Nature Biotechnology, describes an innovative ...
Genetic editing holds promise to treat incurable diseases, but the most popular method—CRISPR—sometimes does more harm than good. A new study from University of California San Diego and Yale University researchers highlights ...
A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones. However, the process carries a small chance of inserting errors that could be ...
When cells are healthy, we don't expect them to suddenly change cell types. A skin cell on your hand won't naturally morph into a brain cell, and vice versa. That's thanks to epigenetic memory, which enables the expression ...
Researchers from the Belgian Federal Institute Sciensano, as part of the DARWIN project, have developed a proof-of-concept for next generation detection methods of genome-edited organisms.
Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential housekeeping process, autophagy ...
