Cell therapies for cancer can be potentially enhanced using a CRISPR RNA-editing platform, according to a new study published Feb. 21 in Cell.
The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes ...
Uncovering the biochemical mechanisms underlying different types of cell death has the potential to provide targets for the treatment of various diseases. A physiological cytokine combination (TNF+IFNγ) has been identified ...
The global challenge of plant disease outbreaks under low light intensities leads to significant crop yield losses, with the mechanisms of low light's impact on plant defense poorly understood. Research has identified high ...
In a study published in MedComm—Biomaterials and Applications Professor Changyang Gong and his Ph.D. student Shiyao Zhou elaborate on the mechanism of CRISPR/Cas9 system. The CRISPR/Cas9 system consists of Cas9 protein ...
Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.
A team of scientists from the University of Ottawa and researchers from other universities and research centers around the world has discovered that 7-dehydrocholesterol (7-DHC) is an endogenous suppressor of ferroptosis, ...
Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells. In fact, the first CRISPR-based therapeutic was recently approved ...
A new CRISPR-Cas toolkit, dubbed "pAblo·pCasso," is set to transform the landscape of bacterial genome editing, offering unprecedented precision and flexibility in genetic engineering. The new technology, developed by researchers ...
In a study published in Nature Biotechnology, Gao Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a series of new prime editors based on the Cas12a ...
