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Cell & Microbiology Jan 14, 2020

A simple twist of cell fate

How do a couple of universally expressed proteins in stem cells and developing embryos influence an individual cell's ultimate fate—whether it ultimately becomes, for example, a retinal cell, a heart muscle cell, or a stomach ...

Veterinary medicine Jan 9, 2020

Doctors come together to save eyesight of 3-year-old gorilla

Animal care specialists at the San Diego Zoo Safari Park were concerned when they noticed cloudiness in the left eye of Leslie, a three-year-old female western lowland gorilla. Closer inspection confirmed the lens had changed ...

Bio & Medicine Dec 6, 2019

Nanocontainer ships titan-size gene therapies and drugs into cells

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size—even hefty ones attached to the gene-editing ...

Space Exploration Dec 2, 2019

When space travel is a blur

Canadian scientists are working on a new way to measure the mechanics of the human eye to better identify astronauts at risk of developing ocular damage before they go into space. Collaborating with the Canadian Space Agency ...

Evolution Oct 17, 2019

How human brain development diverged from great apes

Researchers from the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, Institute of Molecular and Clinical Ophthalmology Basel, and ETH Zurich, Switzerland, have presented new insights into the development ...

Evolution Oct 16, 2019

Scientists discover skin keeps time independent of the brain

Squids, octopuses, cuttlefish, amphibians, and chameleon lizards are among the animals that can change the color of their skin in a blink of an eye. They have photoreceptors in their skin that operate independently of their ...

Molecular & Computational biology Oct 15, 2019

Understanding how human cell types develop, vary between individuals, and fail in disease

We are in the midst of a fascinating journey to understand the cellular phenotypes that compose human bodies and how the human genome is used to build and maintain each cell. "To catalog our human cell types, to understand ...

Biotechnology Oct 15, 2019

AAV vector integration into CRISPR-induced DNA breaks

To design safe clinical trials, it is crucial to better understand and predict gene editing outcomes in preclinical studies. Bence György and collaborators have shown that adeno-associated viruses (AAVs) can stably integrate ...

Optics & Photonics Oct 4, 2019

Optical imager poised to improve diagnosis and treatment of dry eye disease

Researchers have developed a new non-invasive optical imaging system that promises to improve diagnosis and treatments for dry eye disease. Dry eye, which often causes irritation and blurred vision, occurs when there is instability ...

Bio & Medicine Sep 9, 2019

Tiny capsules offer alternative to viral delivery of gene therapy

New tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral infections. But the typical method for delivering gene therapies to specific tissues in the body ...

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