Search results for CRISPR-Cas9

Biotechnology Apr 20, 2021

Genome editing in farm animals: Chickens and pigs with integrated genetic scissors

Researchers at the TUM have demonstrated a way to efficiently study molecular mechanisms of disease resistance or biomedical issues in farm animals. Researchers are now able to introduce specific gene mutations into a desired ...

Biotechnology Apr 13, 2021

Scaling up genome editing in tiny worms

Understanding the effects of specific mutations in gene regulatory regions—the sections of DNA and RNA that turn genes on and off—is important to unraveling how the genome works, as well as normal development and disease. ...

Biotechnology Apr 12, 2021

Researchers call for greater awareness of unintended consequences of CRISPR gene editing

Researchers at the Francis Crick Institute have revealed that CRISPR-Cas9 genome editing can lead to unintended mutations at the targeted section of DNA in early human embryos. The work highlights the need for greater awareness ...

Biotechnology Apr 9, 2021

New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged

Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to organisms' DNA. While the system could potentially be useful in treating a ...

Plants & Animals Apr 7, 2021

Research suggests eucalyptus trees can be genetically modified not to invade native ecosystems

Eucalyptus, a pest-resistant evergreen valued for its hardy lumber and wellness-promoting oil, can be genetically modified not to reproduce sexually, a key step toward preventing the global tree plantation staple from invading ...

Biotechnology Apr 6, 2021

Japanese consumers more concerned about gene-editing of livestock than of vegetables, survey shows

A statistically rigorous survey of Japanese consumers has found that they have more negative opinions about the use of new gene-editing techniques on livestock than they do about use of the same technologies on vegetables.

Biotechnology Apr 5, 2021

CRISPR-SNP-chip enables amplification-free electronic detection of single point mutations

Keck Graduate Institute (KGI) Assistant Professor and University of California, Berkeley Visiting Scientist Dr. Kiana Aran first introduced the CRISPR-Chip technology in 2019. Now just two years later, she has expanded on ...

Biotechnology Mar 29, 2021

Study reports six novel variants for CRISPR-Cas12a in plants, expanding genome engineering

In a new publication in Nature Communications, associate professor of Plant Science at the University of Maryland Yiping Qi continues to innovate genome editing and engineering in plants, with the ultimate goal of improving ...

Cell & Microbiology Mar 26, 2021

Slc20a1b is essential for hematopoietic stem/progenitor cell expansion in zebrafish

Hematopoietic stem/progenitor cells (HSPCs) include hematopoietic stem cells and several lineage-biased hematopoietic progenitor cells, which can provide all blood cell types in an adult organism. Among them, hematopoietic ...

Biotechnology Mar 22, 2021

Upgrade for CRISPR/Cas: Researchers knock out multiple genes in plants at once

Using an improved version of the gene editing tool CRISPR/Cas9, researchers knocked out up to twelve genes in plants in a single blow. Until now, this had only been possible for single or small groups of genes. The approach ...

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