Search results for CRISPR-Cas9

Molecular & Computational biology Aug 18, 2022

The complex origins of Apiaceae and the current state of research

Recently, scientists from Nanjing Agricultural University summarized the current state of Apiaceae research, including traditional and molecular breeding practices, bioactive compounds, medicinal applications, nanotechnology, ...

Biotechnology Aug 9, 2022

Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability

CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...

Cell & Microbiology Aug 8, 2022

Enhancers cooperate to regulate master transcription factors for sound receptor hair cell development

A study published in PNAS on Aug. 5 reveals the genome-wide chromatin accessibility of neonatal cochlear hair cells (HCs) and has identified two previously unknown Atoh1 enhancers. This study demonstrates that three Atoh1 ...

Biotechnology Jul 18, 2022

Synthetic tools conduct messages from station to station in DNA

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

Cell & Microbiology Jul 11, 2022

Hidden genes may be tapped for new antibiotics

Silents are potentially golden in the search for antibiotics to slow the ongoing crisis of resistance in the treatment of disease.

Ecology Jul 8, 2022

Genetically-enhanced biocontrols could help fight large invasive mammals

Invasive alien mammals can have catastrophic impacts on native flora and fauna, causing species extinctions and driving profound environmental change. Classical control methods such as poison baiting, trapping, or hunting ...

Cell & Microbiology Jul 6, 2022

A potential danger of CRISPR gene editing—and why base editing may be safer

Gene therapy using CRISPR/Cas9 gene editing is currently in clinical trials around the world for a variety of diseases. A report from Boston Children's Hospital, published June 27 in Nature Communications, warns of a potential, ...

Biotechnology Jul 1, 2022

'Soft' CRISPR may offer a new fix for genetic defects

Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their ...

Bio & Medicine Jun 23, 2022

Lipid nanoparticles carry gene-editing cancer drugs past tumor defenses

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult. Now, scientists at UT Southwestern have developed nanoparticles ...

Biotechnology Jun 23, 2022

A fine-tuned gene editor that minimizes adverse consequences

The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach ...

page 38 from 40