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Biotechnology Sep 3, 2021

Researchers develop an engineered 'mini' CRISPR genome editing system

The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he ...

Cell & Microbiology Sep 3, 2021

Wired for efficiency: How methanogenic microbes manage electrons

Methanogenic archaea use sophisticated enzyme systems to live in energy-limited anoxic environments. A key mechanism for saving energy is electron bifurcation, a reaction that 'splits' the energy of a pair of electrons, making ...

Evolution Aug 25, 2021

Evolutionary 'time travel' reveals enzyme's origins, possible future designs

"The distinction between the past, present and future is only a stubbornly persistent illusion," Albert Einstein wrote. Perhaps this is nowhere more evident than in protein evolution, where past and present versions of the ...

Evolution Aug 11, 2021

Extremophiles: Resilient microorganisms that help us understand our past and future

In the infamous words of Jurassic Park consultant Dr. Ian Malcolm, "life finds a way". In the depths of the ocean, in volcanic springs, under four meters of ice: almost anywhere scientists can think of to look for life on ...

Cell & Microbiology Jul 27, 2021

Giant amoeba-infecting viruses rely on DNA-packing proteins

For some giant viruses, a DNA-packing trick may be essential for infectivity.

Cell & Microbiology Jul 21, 2021

Giant extrachromosomal elements found in methane-metabolizing archaea

A team of researchers from the University of California, Colorado State University and Lawrence Berkeley National Laboratory has discovered a new kind of extrachromosomal element (ECE) living inside of a methane-metabolizing ...

Earth Sciences Jul 16, 2021

Study examines the role of deep-sea microbial predators at hydrothermal vents

The hydrothermal vent fluids from the Gorda Ridge spreading center in the northeast Pacific Ocean create a biological hub of activity in the deep sea. There, in the dark ocean, a unique food web thrives not on photosynthesis ...

Cell & Microbiology Jul 14, 2021

Oldest fossils of methane-cycling microbes expand frontiers of habitability on early Earth

A team of international researchers, led by the University of Bologna, has discovered the fossilized remains of methane-cycling microbes that lived in a hydrothermal system beneath the seafloor 3.42 billion years ago.

Cell & Microbiology Jul 14, 2021

Photorhabdus virulence cassette as a causative agent in photorhabdus asymbiotica

PVC effectors Pdp1 (a new family of widespread dNTP pyrophosphatase effector in eCIS) and Pnf (a deamidase effector) are loaded inside the inner tube lumen in a "peas-in-the-pod" mode. Moreover, Pdp1 and Pnf can be directly ...

Paleontology & Fossils Jul 13, 2021

DNA from 1,600-year-old Iranian sheep mummy brings history to life

A team of geneticists and archeologists from Ireland, France, Iran, Germany, and Austria has sequenced the DNA from a 1,600-year-old sheep mummy from an ancient Iranian salt mine, Chehrābād. This remarkable specimen has revealed ...

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