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Cell & Microbiology Nov 19, 2018

Activating a new understanding of gene regulation

Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...

Bio & Medicine Nov 15, 2018

Targeted delivery: Cancer identity technology makes it easier to find a tumor's 'address'

Purdue University researchers have developed a technology aimed at making it easier to deliver cancer treatment to the right "address" in the body while also easing the painful side effects of chemotherapy on patients.

Biochemistry Nov 7, 2018

Researchers have unlocked secrets about engineered protein receptor, CAR

Cancer remains the second-leading cause of death in the United States. This year, an estimated 1.7 million new cases will be diagnosed, with nearly 610,000 people expected to die from the disease, according to the National ...

Cell & Microbiology Oct 22, 2018

Understanding architecture of cancer-linked BAF protein complexes provides insight into disease

In 2013, Broad Institute member Cigall Kadoch, then a postdoctoral researcher at Stanford University, discovered that approximately 20 percent of all human cancers involve mutations in a group of proteins called BAF, a complex ...

Plants & Animals Oct 11, 2018

New clinical trials seek treatments for canine cancers, may offer clues on human cancers

Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs ...

Plants & Animals Oct 5, 2018

Study focused on improving radiation treatment for cancers in pet dogs

Can scientists improve cancer treatment for man's best friend?

Biotechnology Oct 5, 2018

Cryptography techniques to screen synthetic DNA could help prevent the creation of dangerous pathogens

In 2016, synthetic biologists reconstructed a possibly extinct disease, known as horsepox, using mail-order DNA for around $100,000. The experiment was strictly for research purposes, and the disease itself is harmless to ...

Business Oct 1, 2018

Drugmaker Pfizer's CEO Read to be replaced by COO Bourla

The biggest U.S.-based drugmaker will change leaders in January when Pfizer Chief Operating Officer Albert Bourla replaces CEO Ian Read, who has led the company for nearly eight years.

Cell & Microbiology Oct 1, 2018

Unveiling the mechanism protecting replicated DNA from degradation

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein ...

Biotechnology Aug 28, 2018

New cancer treatment uses enzymes to boost immune system and fight back

Researchers at The University of Texas at Austin have developed a new approach to treating cancer using enzyme therapy.

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