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Bio & Medicine Aug 21, 2020

Tiny engineered therapeutic delivery system safely solves genetic problems in mice

Inserting genetic material into the body to treat diseases caused by gene mutations can work, scientists say—but getting those materials to the right place safely is tricky.

Biotechnology Aug 7, 2020

Scientists use CRISPR to knock down gene messages early in development

Since its discovery, scientists have been using the much-lauded gene editing tool CRISPR to alter the DNA of model organisms and uncover the functions of thousands of genes. Now, researchers at the Stowers Institute for Medical ...

Cell & Microbiology Aug 6, 2020

Scientists discover new concept of bacterial gene regulation

Bacteria are always with us: These tiny organisms are found within and on our body as is the case with all animals and plants. As part of a healthy microbiome they ensure our wellbeing. But if the microbial community gets ...

Biochemistry Aug 3, 2020

Anatomy of an acne treatment

Sarecycline, a drug approved for use in the United States in 2018, is the first new antibiotic approved to treat acne in more than 40 years. Now, researchers at Yale and the University of Illinois-Chicago have discovered ...

Molecular & Computational biology Jul 29, 2020

Researchers discover 'Marie Kondo' protein which aids in organizing fruit fly embryos

Researchers at the University of Colorado School of Medicine have discovered a protein in fruit fly embryos, dubbed Marie Kondo, that destroys maternal proteins. Much like namesake, author and clutter consultant Marie Kondo, ...

Plants & Animals Jul 28, 2020

The amazing travels of small RNAs

In most organisms, small bits of RNA play a key role in gene regulation by silencing gene expression. They do this by targeting and docking onto complementary sequences of gene transcripts (also RNA molecules), which stop ...

Other Jul 23, 2020

PolyA-miner assesses the effect of alternative polyadenylation on gene expression

Researchers with an interest in unraveling gene regulation in human health and disease are expanding their horizons by closely looking at alternative polyadenylation (APA), an under-charted mechanism that regulates gene expression.

Plants & Animals Jul 14, 2020

Starfish provide missing link in evolution of key brain messenger molecules

Cells in our nervous system, or neurons, communicate with other cells by releasing chemical messengers, which bind to receptor proteins on neighboring cells and change their activity. Neuropeptides are one type of chemical ...

Biotechnology Jul 2, 2020

Tiny mineral particles are better vehicles for promising gene therapy

University of Wisconsin–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination—including a COVID-19 vaccine from Moderna ...

Astronomy Jul 1, 2020

Coronae of supermassive black holes may be the hidden sources of mysterious cosmic neutrinos seen on Earth

The origin of high-energy cosmic neutrinos observed by the IceCube Neutrino Observatory, whose detector is buried deep in the Antarctic ice, is an enigma that has perplexed physicists and astronomers. A new model could help ...

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