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Biochemistry Sep 14, 2022

Dense and permeable: Molecular organization of tight junctions decoded

They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction is associated with diseases. Although their molecular ...

Optics & Photonics Sep 9, 2021

Microscopy plus AI equals rapid COVID-19 detection: study

Beckman researchers paired microscopy with artificial intelligence to develop a COVID-19 test that's fast, accurate, and cost-effective. All we need to do is say "ahh."

Optics & Photonics May 17, 2021

Diamonds engage both optical microscopy and MRI for better imaging

When doctors or scientists want to peer into living tissue, there's always a trade-off between how deep they can probe and how clear a picture they can get.

Optics & Photonics Jan 4, 2021

New microscopy technique images live cells with 7 times greater sensitivity

Experts in optical physics have developed a new way to see inside living cells in greater detail using existing microscopy technology and without needing to add stains or fluorescent dyes.

Analytical Chemistry Sep 9, 2019

Researchers develop new interferometric single-molecule localization microscopy

Various image-based central position estimation (termed "centroid fitting") methods such as 2-D Gaussian fitting methods have been commonly used in single-molecule localization microscopy (SMLM) to precisely determine the ...

Materials Science Feb 25, 2019

New imaging technique reveals how mechanical damage begins at the molecular scale

Just as a journey of 1,000 miles begins with a single step, the deformations and fractures that cause catastrophic failure in materials begin with a few molecules torn out of place. This in turn leads to a cascade of damage ...

Optics & Photonics Apr 24, 2017

Chip-based nanoscopy: Microscopy in HD quality

Physicists at Bielefeld University and the Arctic University of Norway in Tromsø have developed a photonic chip that makes it possible to carry out super-resolution light microscopy, also called 'nanoscopy,' with conventional ...

Cell & Microbiology Feb 1, 2024

New research shows that the arrangement of bacteria in biofilms affects their sensitivity to antibiotics

Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms.

Plants & Animals Nov 24, 2023

Wing characteristics of primitive insects unraveled

Mayflies are ancient insects that possess a unique life stage not found in other winged insects: Their fully-grown nymphs develop into a winged subadult stage, the so-called subimago, which is not yet capable of reproduction ...

Cell & Microbiology Sep 22, 2023

Researchers reveal composition and regulatory mechanism of the nucleolar vacuole in C. elegans

A team led by Prof. Guang Shouhong and Prof. Feng Xuezhu from the University of Science and Technology (USTC) of the Chinese Academy of Sciences (CAS) revealed, for the first time, the composition and regulatory mechanism ...

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