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Search results for fluorescence microscopy

Biotechnology Dec 7, 2022

Three-in-one microscope allows researchers to target biomolecules

Physicists from TU Delft have developed a three-in-one microscope in which a light beam, electron beam and ion beam work together to precisely cut out specific slices from biological samples.

Optics & Photonics Dec 5, 2022

Team develops photon-efficient volumetric imaging method with light-sheet scanning fluorescence microscopy

In biological imaging, researchers aim to achieve 3D, high-speed, and high-resolution, with low photobleaching and phototoxicity. The light-sheet fluorescence microscope (LSFM) helps meet that aim. Based on a unique excitation ...

Biochemistry Dec 1, 2022

Integrated platform promises to accelerate drug discovery process

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.

Cell & Microbiology Nov 17, 2022

Quantitative characterization of filamentous fungal promoters to discover cryptic natural products

Natural products (NPs) are low-molecular-weight compounds derived from secondary metabolic pathways, which are regulated by hierarchical regulatory networks from cluster-specific regulators to global transcriptional complexes.

Biotechnology Nov 16, 2022

High-resolution microscopy for analysis of protein complexes

Researchers at Forschungszentrum Jülich and the Berlin Institute of Health at Berlin's Charité Hospital have developed a novel method for determining the number of subunits within protein complexes. The method is a further ...

Cell & Microbiology Nov 11, 2022

Researchers open door to stain-free labeling of cellular components

Scientists at EPFL and the Consiglio Nazionale delle Ricerche (CNR), the University Federico II, and CEINGE-Biotecnologie avanzate in Naples, Italy, have developed a new method to screen individual cells quickly and reliably ...

Optics & Photonics Nov 3, 2022

A new approach for high-throughput quantitative phase microscopy

Cell organelles are involved in a variety of cellular life activities. Their dysfunction is closely related to the development and metastasis of cancer. Exploration of subcellular structures and their abnormal states facilitates ...

Cell & Microbiology Nov 3, 2022

Defect in cellular respiration renders sac fungi infertile

If a fungus has to take a circuitous route to achieve cellular respiration, it lacks the energy to build fruiting bodies.

Optics & Photonics Nov 1, 2022

Overcoming the optical resolution limit

When measuring with light, the lateral extent of the structures that can be resolved by an optical imaging system is fundamentally diffraction limited. Overcoming this limitation is a topic of great interest in recent research, ...

Earth Sciences Nov 1, 2022

Scientists uncover new clues about the climate and health impact of secondary organic aerosol particles

Peering inside common atmospheric particles is providing important clues to their climate and health effects, according to a new study by University of British Columbia chemists.

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