Malaria remains one of the biggest global public health challenges. It kills a young child every two minutes, more than any other infectious disease.
For many diseases, the tools of medicine are reaching their limits. CRISPR technologies open new avenues for diagnostics and therapies, although the natural source of CRISPR remains largely untapped. Scientists from the Helmholtz ...
Recently, scientists from the University of Tsukuba developed a novel CRISPR/Cas9-based genome-editing tool called Target activation-induced cytidine deaminase (Target-AID). They targeted SlDELLA and SlETR in the model ...
Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) should accelerate their development—as well ...
Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field. The work appears ...
In recent work, researchers from the Beijing Academy of Agriculture and Forestry Sciences and the Chinese Academy of Sciences characterized the molecular mechanism of color formation in an orange-fruited tomato inbred line, ...
Since the discovery of CRISPR/Cas9, also known as molecular scissors, scientists around the world have been working to improve the revolutionary technique for altering DNA that earned Emmanuelle Charpentier and Jennifer Doudna ...
CRISPR-Cas9, the "genetic scissors," creates new potential for curing diseases, but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that ...
Around the world, populations of many beloved species are declining at increasing rates. According to one grim projection, as many as 40% of the world's species may be extinct by 2050. Alarmingly, many of these declines are ...
Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...
