Search results for CRISPR

Molecular & Computational biology Feb 14, 2022

Compressing gene libraries to expand accessibility, research opportunities

In image compression, a large file that could be cumbersome to store or share loses a small amount of visual information. This "lossiness" largely preserves the image while vastly reducing its file sizeā€”and serves as the ...

Biotechnology Feb 2, 2022

CRISPR-Cas9 can generate unexpected, heritable mutations

CRISPR-Cas9, the "genetic scissors," creates new potential for curing diseases, but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that ...

Cell & Microbiology Jan 21, 2022

Increasingly efficient production of human pluripotent stem cells

Researchers at the University of Helsinki have developed a new, faster and more reliable technique for reverting human cells to the stem cell state. Pluripotent stem cells are a key tool in biomedicine for modeling various ...

Molecular & Computational biology Jan 19, 2022

Discovery of a 'hidden gem' enables gene editing with a small but mighty CRISPR-Cas3 system

Nearly a decade ago, scientists discovered the power of CRISPR, a tool employed by bacteria to protect themselves against viral invaders. This system is now a fundamental research tool used for editing genomes. One of most ...

Cell & Microbiology Jan 17, 2022

Molecular mechanism involved in the cholesterol cell transport

A team of the University of Barcelona (UB) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) identified a mechanism involved in the movement of cholesterol inside the cells. The study, published in the Journal ...

Cell & Microbiology Jan 13, 2022

Human proteins behind COVID-19 infection revealed by innovative CRISPR technology

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, ...

Molecular & Computational biology Jan 12, 2022

Scientists expand CRISPR-Cas9 genetic inheritance control in mammals

Nearly three years ago University of California San Diego researchers announced the world's first CRISPR-Cas9 genetic editing-based approach to controlling inheritance in mammals.

Biotechnology Jan 5, 2022

Researchers pioneer new method to edit genes in human cells

Over the past decade, the CRISPR genome-editing system has revolutionized molecular biology, giving scientists the ability to alter genes inside living cells for research or medical applications. Now, researchers at Gladstone ...

Molecular & Computational biology Dec 28, 2021

Researchers develop specific and sensitive Cas12c-based nucleic acid detection platform

The prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated (CRISPR/Cas) protein system has been reconstructed for a revolutionary targeted genome modification platform and nucleic ...

Molecular & Computational biology Dec 23, 2021

Translocation on chromosome 6 causes abnormalities during meiosis and fewer seeds in watermelon

Watermelon (Citrullus lanatus) is an economically important horticultural crop and one of the top five most widely consumed fresh fruits in the world. Compared with traditional seeded cultivars, seedless watermelon is preferred ...

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