Search results for CRISPR

Molecular & Computational biology Mar 25, 2022

How bacteria 'self-vaccinate' against viral invaders

Like most organisms, bacteria are preyed upon by viruses—and their go-to approach to destroying the invaders is to simply chop them up. As soon as it sees a virus, a bacterium may employ a host of immune strategies to slice ...

Cell & Microbiology Mar 22, 2022

New CRISPR element regulates viral defense

What tasks need to be done today, and which is the most urgent? People have to constantly set priorities in their daily life. Bacteria are no different: They too must prioritize when combating viruses with CRISPR. However, ...

Molecular & Computational biology Mar 14, 2022

A potential therapy for muscular dystrophy: Using mRNA delivery to improve muscle strength

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, ...

Molecular & Computational biology Mar 9, 2022

Beyond CRISPR: New DNA tools rewrite genes to fight diseases like COVID-19

When Emmanuelle Charpentier and Jennifer Doudna won the Nobel Prize in Chemistry in 2020, their CRISPR gene editor had revolutionized medicine, agriculture, and genetics in just a few short years. But already, plans were ...

Plants & Animals Mar 9, 2022

Forget mammoths—These researchers are exploring bringing back the extinct Christmas Island rat

Dinosaurs went extinct 65 million years ago, mammoths 4,000 years ago, and the Christmas Island Rat 119 years ago. Since becoming a popular concept in the 1990s, de-extinction efforts have focused on grand animals with mythical ...

Biotechnology Mar 8, 2022

Studying diseases with better delivery of gene-editing tools

Stem cells can be used to study the effects of disease on numerous tissue types due to their pluripotency, or ability to produce cells of any type. But using gene-editing tools with them can be challenging, according to Xiaojun ...

Biotechnology Mar 2, 2022

Gene editing gets safer thanks to redesigned Cas9 protein

One of the grand challenges with using CRISPR-based gene editing on humans is that the molecular machinery sometimes makes changes to the wrong section of a host's genome, creating the possibility that an attempt to repair ...

Molecular & Computational biology Feb 25, 2022

New approach enables faster characterization of CRISPR immune systems

For many diseases, the tools of medicine are reaching their limits. CRISPR technologies open new avenues for diagnostics and therapies, although the natural source of CRISPR remains largely untapped. Scientists from the Helmholtz ...

Plants & Animals Feb 17, 2022

CROPSR: A new tool to accelerate genetic discoveries in crops

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) should accelerate their development—as well ...

Biotechnology Feb 15, 2022

Gene editing now possible in ticks

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field. The work appears ...

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