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Search results for fluorescence microscopy

Cell & Microbiology Mar 30, 2023

Shining a light on the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon—when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process. ...

Optics & Photonics Mar 20, 2023

Gigapixel 3D microscope captures life in unprecedented detail

When a couple of plucky graduate students took the first picture with their pieced-together microscope, it turned out better than they'd hoped. Sure, there was a hole in one section and another was upside down—but they could ...

Optics & Photonics Mar 20, 2023

Speckle-illumination proves useful in photoacoustic microscopy

Motivated by the limitations of scanning approaches to photoacoustic microscopy, an international group supervised by Emmanuel Bossy of Université Grenoble Alpes experimented with structured illumination using known and unknown ...

Optics & Photonics Mar 20, 2023

Coherent Raman microscopy could be expanded through fusion of instruments and computers

Raman scattering is an inelastic scattering process that exchanges energies between photons and molecules to carry information on molecular vibrations. Raman micro-spectroscopy has become an indispensable analytical tool ...

Optics & Photonics Mar 10, 2023

A super-resolution microscopy method for rapid differentiation of molecular structures in 3D

Super-resolution microscopy methods are essential for uncovering the structures of cells and the dynamics of molecules. Since researchers overcame the resolution limit of around 250 nanometers (while winning the 2014 Nobel ...

Cell & Microbiology Mar 10, 2023

New research to bring Brillouin microscopy closer to widespread use in diagnostic medicine

Diagnostic imaging offers physicians and scientists critical visual representations of internal body structures, greatly enhancing clinical analysis and medical intervention. Researchers continue to break new ground on how ...

Optics & Photonics Mar 10, 2023

High-speed super-resolution microscopy via temporal compression

As an indispensable tool for observing the microcosmos, optical microscopy has boosted the development of various fields, including biology, medicine, physics, and materials. However, optical diffraction imposes a spatial ...

Molecular & Computational biology Mar 10, 2023

Study uncovers aspect of how muscular dystrophies progress

A research study has shed new light on how congenital muscular dystrophies such as Walker-Warburg syndrome progress, bringing hope for better understanding, early diagnosis and treatments of these fatal disorders.

Biotechnology Mar 10, 2023

Major advance in super-resolution fluorescence microscopy

Scientists led by Nobel Laureate Stefan Hell at the Max Planck Institute for Medical Research in Heidelberg have developed a super-resolution microscope with a spatio-temporal precision of one nanometer per millisecond. An ...

Biotechnology Mar 9, 2023

Precise transcript targeting by CRISPR-Csm complexes

Mammalian cells are inherently complex due to subcellular compartments, thereby making the process of robust transcript targeting of nucleic acids somewhat challenging in the molecular biology lab. In a recent report now ...

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