ETH researchers have drastically improved existing proteomics techniques so they can capture all functional alterations in proteins. Their work paves the way for using these signatures as diagnostic tools.
Bringing together soft, malleable living cells with hard, inflexible electronics can be a difficult task. UChicago researchers have developed a new method to face this challenge by utilizing microscopic structures to build ...
Insofar as variants for mitochondrial disease are supposed to be rare in the genome, don't think for even a minute that it can't happen to you. In fact, the closer one looks at the full mitonuclear genomes of normal folks, ...
Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases.
Mitochondria are cellular organelles that generate most of the energy cells need to function, and thus play an important role in maintaining cell health. In a new study, researchers from Osaka University discovered a novel ...
Ribosomes are the machines in the cell that use instructions from mRNA to synthesize functional proteins. There are hundreds of thousands of ribosomes in each cell, and they mostly process their instructions faithfully. But ...
Researchers have identified the driving force behind a cellular process linked to neurodegenerative disorders such as Parkinson's and motor neurone disease.
Alzheimer's disease and Parkinson's disease are both examples of amyloid diseases, where malfunctioning proteins accumulate to form fibrils and larger aggregates called amyloid plaques. In the journal Biophysical Chemistry ...
Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.
Cells require a balance among oxidation-reduction reactions, or redox homeostasis. Loss of that balance to create oxidative stress is often associated with neurodegeneration. Less is known about how loss of that balance at ...
