Search results for organ-on-a-chip applications

Environment Apr 17, 2024

Research group runs simulations capable of describing South America's climate with unprecedented accuracy

A consortium made up of researchers from more than ten countries, including Brazil, the United States and some European nations, is running simulations of the past and future climate in South America with unprecedented resolution. ...

Cell & Microbiology Aug 29, 2019

Pancreas on a chip: Scientists combine organ-on-a-chip and stem-cell technologies

By combining two powerful technologies, scientists are taking diabetes research to a whole new level. In a study led by Harvard University's Kevin Kit Parker, microfluidics and human, insulin-producing beta cells have been ...

Biotechnology Aug 28, 2019

Organ-on-a-chip: 3-D self-rolled biosensor array to electrically interrogate electrogenic cells

Cell to cell communication plays an important role in coordinating the function of biological systems. Three-dimensional (3-D) spheroids (cell aggregates) allow biologists to explore cellular communication during tissue development ...

Analytical Chemistry Oct 5, 2017

Scientists develop 'body-on- a-chip' system to accelerate testing of new drugs

Using the same expertise they've employed to build new organs for patients, scientists at Wake Forest Institute for Regenerative Medicine and colleagues have engineered micro hearts, lungs and livers that can potentially ...

Analytical Chemistry Jan 17, 2019

3-D culturing hepatocytes on a liver-on-a-chip device

Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...

Nanophysics Jun 21, 2021

A cavitation-on-a-chip device with a multiple microchannel configuration

Hydrodynamic cavitation is a major phase change phenomena that can occur with a sudden decrease in the local static pressure within a fluid. The emergence of microelectromechanical systems (MEMS) and high-speed microfluidic ...

Biotechnology Jan 16, 2018

'Heart-on-a-chip' process aims to speed up drug testing

Testing new clinical drugs' effect on heart tissue could become quicker and more straightforward, thanks to new research from Harvard University.

Analytical Chemistry Feb 8, 2017

Scientists create organs-on-chips for large-scale drug screening

Led by UCI professor of molecular biology & biochemistry Christopher C.W. Hughes, the research team successfully established multiple vascularized micro-organs on an industry-standard 96-well plate. Hughes and the study's ...

Biotechnology Jun 17, 2019

Inducing an osteoarthritic (OA) phenotype in a cartilage-on-a-chip (COC) model

In an aging population, the social impact of osteoarthritis (OA) can dramatically increase to become the most common musculoskeletal disease. However, at present, therapies are limited to palliative treatments or surgical ...

Cell & Microbiology Feb 7, 2023

Biosensor could lead to new drugs, sensory organs on a chip

A synthetic biosensor that mimics properties found in cell membranes and provides an electronic readout of activity could lead to a better understanding of cell biology, development of new drugs, and the creation of sensory ...

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