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Biotechnology Apr 11, 2023

New method tracks gene expression in single cells over space and time

RNA plays a central role in biology, but there is still much to learn about the molecule's life cycle in the cell. In recent years, scientists have devised methods that can take snapshots of messenger RNAs (mRNAs) scattered ...

Cell & Microbiology Apr 7, 2023

Simple but revolutionary modular organoids created with hydrogels

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without ...

Cell & Microbiology Apr 5, 2023

Growing cells on synthetic PIC gel could save millions of mice

The synthetic PIC gel, discovered in 2013 by Radboud University chemists, appears to behave like collagen. This makes the gel very useful for studying interactions between cells and their immediate environment. In practice, ...

Cell & Microbiology Mar 28, 2023

Skin-on-a-chip: Modeling an innervated epidermal-like layer on a microfluidic chip

Bioengineers and tissue engineers intend to reconstruct skin equivalents with physiologically relevant cellular and matrix architectures for basic research and industrial applications. Skin pathophysiology depends on skin-nerve ...

Agriculture Mar 24, 2023

Tiny but mighty: Microgreens could play an important role in feeding a sustainable future

Feeding 8 billion humans requires ingenuity and innovation. Zhenlei Xiao is an associate professor in residence in the UConn's College of Agriculture, Health and Natural Resources Department of Nutritional Sciences and her ...

Analytical Chemistry Mar 21, 2023

Researchers develop portable color-changing food spoilage sensor

When foods like fish, meat, and cheese decompose, they release a variety of low molecular weight organic nitrogen compounds known as biogenic amines (BAs). While the body uses BAs in small amounts in processes like hormone ...

Cell & Microbiology Mar 13, 2023

Methods for growing skeletal muscle tissue from stem cells to help understand disease

Head of the Crick's Stem Cells and Neuromuscular Regeneration Lab, Francesco Saverio Tedesco, is also a doctor at Great Ormond Street Hospital, where he specializes in neurological and neuromuscular diseases of childhood, ...

Cell & Microbiology Mar 13, 2023

Single-cell sequencing solution seeks to unleash disruptive science, with a vortexer

A new single-cell encapsulation, lysis and barcoding method of cDNA is faster and requires less equipment, hardware, expense and expertise. It has been demonstrated to be compatible and scalable with any size container, from ...

Analytical Chemistry Mar 7, 2023

Researchers obtain anion ionic water-soluble two-photon initiator for 3D hydrogel construction

Prof. Zheng Meiling's team from the Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences (CAS) proposed an anion exchange strategy and developed a carbazole-based anion-ion water-soluble two-photon ...

Cell & Microbiology Feb 27, 2023

Growing blood stem cells in the lab to save lives

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type. HSC transplants can be used to treat conditions where bone marrow is damaged and ...

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