Search results for CRISPR-Cas9

Biotechnology Apr 27, 2023

Pulling the plug on viral infections: CRISPR isn't just about cutting

CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses by targeting and destroying viral ...

Plants & Animals Apr 24, 2023

Researchers develop new tools for precise large DNA insertions

Gao Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has developed a new genome editing technology that achieves efficient and precise targeted insertion of ...

Cell & Microbiology Apr 18, 2023

Biologists reveal a scissor enzyme that cuts the chromatin bridge and prevents DNA damage and autoimmunity

A research team led by Dr. Gary Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed the function of a unique enzyme, ANKLE1. ANKLE1 acts on chromatin bridges that are trapped ...

Molecular & Computational biology Apr 12, 2023

Examining early grain development in bread wheat

Bread wheat (Triticum aestivum L.) is a pivotal staple food crop, providing about 20% of calories consumed by humans. Grain weight is one of the three factors of wheat yield, and also the key index of wheat breeding for high ...

Molecular & Computational biology Mar 30, 2023

Toward a tastier tomato: Recovering the lost STP1 variant in modern tomato to improve soluble solid in fruit

In a study recently published in the journal Horticulture Research, researchers performed a genome-wide association study (GWAS) for SSC of the red-ripe fruits in a population consisting of 481 tomato accessions with large ...

Bio & Medicine Mar 30, 2023

New nanoparticles can perform gene-editing in the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

Molecular & Computational biology Mar 28, 2023

Fluorescent visualization and evaluation of NPC1L1-mediated cholesterol absorption at the levels of endocytic vesicles

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease. The absorption of intestinal ...

Evolution Mar 28, 2023

What should we call evolution driven by genetic engineering? Genetic welding, says researcher

With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations. Evolutionary geneticist Asher Cutter proposes that ...

Plants & Animals Mar 22, 2023

Biologists report on alternative life-history strategy in Colias butterflies

Have you ever marveled at the vast diversity of life on our planet, from tiny creatures living only a few hours to majestic beings that can survive for centuries? These differences in lifespan, size, and reproductive age ...

Cell & Microbiology Mar 17, 2023

Klara, a transparent fish for research on aging

The body pigmentation of an organism is caused by coloring substances and structures that are found in the cells of skin, hair, feathers, or scales, for example. This pigmentation considerably limits investigations of important ...

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